​In Alberta, the three regulatory Colleges for nurses agree that LPNs, RPNs, and RNs are authorized under regulation and have the education to administer medications and substances by injection. An order by an authorized prescriber is required before any nurse can administer Schedule 1 medications and/or substances, e.g. neuromodulators and dermal fillers. The nurse is responsible and accountable to have the required competencies (education and experience) to carry out the order.

In addition, The College of Licensed Practical Nurses of Alberta requires that LPNs providing aesthetic nursing procedures within their defined scope of practice must have direct or indirect supervision by a physician. The physician must be trained in dermatology, on-site, and available to assist as necessary when aesthetic procedures and treatments are being performed.